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In summary, dysregulation of immunoregulatory signalling molecules, including cytokines, microglial complement, MET, and MHCI, is an important link in the pathological process of ASD that possibly regulates synaptic morphology and plasticity in the CNS through common downstream pathways

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these proteins have been demonstrated to be involved in adaptor, signaling, and cell polarity functions

Figure 5: Print of Professor Leopold Gmelin, a German chemist

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(2000) Insulin-like growth factor I and growth hormone (GH) treatment in GH-deficient humans: differential effects on protein, glucose, lipid, and calcium metabolism